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FIGURE 4 Darinaparsin was characterized in vitro as a potent inducer of growth arrest and apoptosis in a range of hematologic malignancies such as acute promyelocytic leukemia (APL), acute lymphoblastic leukemia, B cell lymphoma, and multiple myeloma (Matulis et al., 2009)

It is especially useful in conditions where oral supplementation is not suitable or effective, such as in critically ill patients, ICU cases, severe vomiting, or in patients with poor compliance to oral therapy

Unlike full-length human growth hormone, which binds the GH receptor and elevates IGF-1, AOD-9604 acts through a diacylglycerol second-messenger pathway in fat cells

doi: 10.1016/j.actbio.2014.01.020

GLUT4 connects to basic metabolic rate and ideas of fast versus slow metabolism